New paper out in Nature Neuroscience!

A big congratulations to Munib, Jackie, Juan, and Emma on their recent publication! In this landmark work, they assess the separability of cognitive and motor dynamics in mice, develop a novel framework for isolating cognitive and motor dynamics when they are separable, show that dynamics commonly taken to support cognitive processes are strongly contaminated by movements, and more! Check it out now at the links below:

Hasnain MA, Birnbaum JE, Ugarte Nunez JL, Hartman EK, Chandrasekaran C, Economo MN (2025) Separating cognitive and motor processes in the behaving mouse. Nat Neurosci | DOI | pdf

New Review out in the Journal of Neuroscience!

In this review written in collaboration with colleagues at UCSD, RIKEN, and the Technion, Mike explores the mechanisms underlying motor learning across spatial and temporal scales. Recent findings in the dynamic regulation of dendritic spines, the role of perisynaptic astrocyte processes in maintaining synaptic stability, the functional diversity among pyramidal neuron subtypes, and more are all discussed. Check it out at the links below!

Economo MN, Komiyama T, Kubota Y, Schiller J (2024) Learning and Control in Motor Cortex across Cell Types and Scales. J Neurosci | DOI | pdf

New paper out in eNeuro!

Big congrats to Jack for his recent publication! This work derives a model of the relationship between ISI violations and spike-sorting cluster cross-contamination more comprehensive and robust than any previously described, validates and limit tests that model in silico, and then applies it to publicly available spike-sorted electrophysiology datasets. Check it out!

Vincent JP, Economo MN (2024) Assessing Cross-Contamination in Spike-Sorted Electrophysiology Data. eNeuro | DOI | pdf