Next generation electrophysiology with Neuropixels probes allow us to record the activity of hundreds of neurons across many brain regions simultaneously.




Optogenetics is a crucial technology for identifying and recording the activity of discrete cell types in the brain during behavior and for perturbing neural circuits to probe their function.




Large-scale neuroanatomy leveraging new viral, genetic, computational, and imaging tools provides a substrate for new hypotheses of brain function.



GcampIn vivo imaging

Ultra-sensitive fluorescent sensors of both spiking and neurotransmitter/neuromodulator release allow us to monitor the activity of genetically identified neural populations during behavior.




We use single-cell RNA sequencing to identify and ultimately target genetically specified neural populations that have distinct roles in motor control.




We study neural circuits while mice are engaged in goal-directed behavior and use computer vision to measure their movements quantitatively.  Studying tongue and jaw movements gives us a rich and experimentally tractable model for motor control.