Large-scale neuroanatomy leveraging new viral, genetic, computational, and imaging tools provides a substrate for new hypotheses of brain function.
In vivo imaging
We use single-cell RNA sequencing to identify and ultimately target genetically specified neural populations that have distinct roles in motor control.
We study neural circuits while mice are engaged in goal-directed behavior and use computer vision to measure their movements quantitatively. Studying tongue and jaw movements gives us a rich and experimentally tractable model for motor control.